Yes, Diamox is often more effective when it is combined with a good broad-spectrum antibiotic to help prevent secondary infections. Kanamycin is one of the most effective of these, since it works well in saltwater (unlike many other antibiotics) and is absorbed readily through the skin and gills of the seahorse.
Either an open ended air bubbler or an air diffuser can be used to aerate your treatment tank, Tia.
Let me know if you need instructions regarding the best way to administer the Diamox treatments, and I will be happy to provide you with more information in that regard.
Good luck restoring your Tigertail to good health once again, Tia.
Pete Giwojna, Ocean Rider Tech Support